Basic Information
ID: ALA5233411
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5233411
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.63 | 2.79 | 2.79 |
| 440.48 | 1.49 | 1.49 |
| 466.93 | 2.06 | 2.06 |
| 468.54 | 2.18 | 2.18 |
| 480.96 | 2.45 | 2.45 |