Basic Information
ID: ALA5236876
Type: Binding
Description: Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP addition and further incubated for 120 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5236876
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.31 | 3.10 | 3.10 |
| 332.41 | 2.82 | 2.82 |
| 292.34 | 2.33 | 2.33 |
| 431.34 | 3.25 | 3.25 |
| 337.38 | 1.92 | 1.92 |
| 333.40 | 2.40 | 2.40 |
| 323.40 | 2.66 | 2.66 |
| 390.49 | 2.33 | 2.33 |
| 295.35 | 1.27 | 1.27 |
| 295.35 | 2.18 | 2.18 |
| 308.35 | 1.31 | 1.31 |
| 307.36 | 1.91 | 1.91 |
| 310.33 | 2.26 | 2.26 |
| 308.35 | 1.13 | 1.13 |
| 294.32 | 0.92 | 0.92 |
| 293.33 | 1.72 | 1.72 |
| 377.45 | 2.41 | 2.41 |
| 337.38 | 1.92 | 1.92 |
| 322.37 | 2.13 | 2.13 |
| 335.41 | 2.59 | 2.59 |
| 293.33 | 1.52 | 1.52 |
| 309.37 | 2.27 | 2.27 |
| 321.38 | 2.22 | 2.22 |
| 296.33 | 1.58 | 1.58 |
| 307.36 | 1.91 | 1.91 |
| 298.35 | 1.50 | 1.50 |
| 304.31 | 2.17 | 2.17 |
| 297.32 | 0.36 | 0.36 |
| 323.36 | 1.53 | 1.53 |
| 307.36 | 1.73 | 1.73 |
| 378.44 | 1.36 | 1.36 |