Basic Information
ID: ALA5236938
Type: Binding
Description: Inhibition of CDK6/cyclin D1 (unknown origin) assessed as reduction in substrate peptide phosphorylation using DYRKtide peptide as substrate preincubated for 12 mins followed by ATP addition and measured for 45 mins by mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5236938
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.54 | 2.97 | 2.97 |
| 471.53 | 2.04 | 2.04 |
| 421.52 | 1.10 | 1.10 |
| 425.94 | 2.40 | 2.40 |
| 461.59 | 2.42 | 2.42 |
| 419.55 | 2.52 | 2.52 |
| 421.52 | 1.23 | 1.23 |
| 455.97 | 1.76 | 1.76 |
| 391.50 | 1.74 | 1.74 |
| 405.52 | 2.05 | 2.05 |
| 463.60 | 2.67 | 2.67 |
| 405.52 | 2.13 | 2.13 |
| 379.49 | 1.60 | 1.60 |
| 449.58 | 1.93 | 1.93 |
| 435.55 | 1.41 | 1.41 |
| 447.56 | 2.25 | 2.25 |
| 405.52 | 1.99 | 1.99 |
| 485.56 | 1.91 | 1.91 |
| 365.46 | 1.21 | 1.21 |
| 435.55 | 1.28 | 1.28 |
| 430.53 | 1.81 | 1.81 |
| 449.58 | 2.28 | 2.28 |