Basic Information
ID: ALA5237300
Type: Binding
Description: Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as substrate preincubated for 15 mins followed by substrate addition and measured after 5 min in presence of beta-NADPH
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5237300
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.32 | 2.18 | 2.18 |
| 373.46 | 3.35 | 3.35 |
| 335.29 | 2.58 | 2.58 |
| 385.47 | 3.54 | 3.54 |
| 373.46 | 3.35 | 3.35 |
| 374.44 | 2.75 | 2.75 |
| 402.49 | 3.97 | 3.97 |
| 385.47 | 3.66 | 3.66 |
| 386.50 | 4.27 | 4.27 |
| 227.26 | 2.84 | 2.84 |
| 374.44 | 2.75 | 2.75 |
| 404.49 | 4.41 | 4.41 |
| 386.50 | 4.27 | 4.27 |
| 372.47 | 3.96 | 3.96 |
| 386.50 | 4.27 | 4.27 |
| 386.50 | 4.27 | 4.27 |
| 296.37 | 2.65 | 2.65 |
| 374.44 | 2.75 | 2.75 |
| 400.52 | 4.58 | 4.58 |
| 400.52 | 4.92 | 4.92 |
| 373.46 | 3.35 | 3.35 |
| 390.46 | 4.10 | 4.10 |
| 372.47 | 4.18 | 4.18 |
| 293.37 | 3.42 | 3.42 |
| 386.50 | 4.12 | 4.12 |
| 406.91 | 4.61 | 4.61 |
| 371.48 | 4.02 | 4.02 |
| 370.50 | 5.15 | 5.15 |
| 400.52 | 4.58 | 4.58 |
| 324.42 | 3.43 | 3.43 |