Basic Information
ID: ALA5238050
Type: Binding
Description: Protac activity at BRD4/VHL E3 ligase in human MDA-MB-231 cells assessed as decrease in BRD4 expression at 0.1 nM to 10 uM incubated for 8 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: MDA-MB-231
Activity Charts
Bioactivity
Activity Types for Assay ALA5238050
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 785.28 | 3.68 | 3.68 |
| 771.26 | 3.29 | 3.29 |
| 799.31 | 4.07 | 4.07 |
| 840.36 | 3.32 | 3.32 |
| 854.39 | 3.71 | 3.71 |
| 868.42 | 4.10 | 4.10 |