Basic Information
ID: ALA5238070
Type: Binding
Description: Inhibition of N-terminal GST-tagged human wild type ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus-infected Sf21 cells using LANCE Ultra ULight-PolyGT substrate incubated for 2 hrs by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: ALK tyrosine kinase receptor(ALA4247)
Document: ALA5236584
Inhibition of N-terminal GST-tagged human wild type ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus-infected Sf21 cells using LANCE Ultra ULight-PolyGT substrate incubated for 2 hrs by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5238070
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 507.83 | ||
| 496.81 | ||
| 508.82 | ||
| 563.90 | ||
| 508.82 | ||
| 507.83 | ||
| 526.83 | ||
| 563.90 | ||
| 526.83 | ||
| 480.77 |