Metabolic stability of the compound in human liver microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by NADPH ...

Basic Information

ID: ALA5238076

Type: ADME

Description: Metabolic stability of the compound in human liver microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA5236584

Metabolic stability of the compound in human liver microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
450.355.045.04
508.82
480.77