Basic Information
ID: ALA5238200
Type: Toxicity
Description: Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as change in body weight at 50 mg/kg, po once a day measured for 16 days
Format: BAO_0000218
Organism: Mus musculus
Strain: BALB/c
Target: ADMET(ALA612558)
Document: ALA5236589
Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as change in body weight at 50 mg/kg, po once a day measured for 16 days: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5238200
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |
| 526.56 | 4.94 | 4.94 |
| 541.57 | 4.63 | 4.63 |
| 529.54 | 4.96 | 4.96 |
| 485.51 | 4.62 | 4.62 |