Assay Report Card

Basic Information

ID: ALA5238200

Type: Toxicity

Description: Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as change in body weight at 50 mg/kg, po once a day measured for 16 days

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.474.894.89
526.564.944.94
541.574.634.63
529.544.964.96
485.514.624.62