In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume...

Basic Information

ID: ALA5238202

Type: Functional

Description: In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume at 50 mg/kg, po once a day measured for 16 days relative to BI-3406

Format: BAO_0000218

Organism: Homo sapiens

Cell type: MIA PaCa-2

Target:  MIA PaCa-2(ALA614725)

Document:  ALA5236589

In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume at 50 mg/kg, po once a day measured for 16 days relative to BI-3406: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
541.574.634.63