Basic Information
ID: ALA5238203
Type: Functional
Description: In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume at 50 mg/kg, po once a day measured for 16 days relative to control
Format: BAO_0000218
Organism: Homo sapiens
Cell type: MIA PaCa-2
Target: MIA PaCa-2(ALA614725)
Document: ALA5236589
In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume at 50 mg/kg, po once a day measured for 16 days relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5238203
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |
| 526.56 | 4.94 | 4.94 |
| 541.57 | 4.63 | 4.63 |
| 529.54 | 4.96 | 4.96 |