Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as mortality at 50 mg/kg, po once a day measured ...

Basic Information

ID: ALA5238204

Type: Toxicity

Description: Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as mortality at 50 mg/kg, po once a day measured for 16 days

Format: BAO_0000218

Organism: Mus musculus

Strain: BALB/c

Target:  ADMET(ALA612558)

Document:  ALA5236589

Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as mortality at 50 mg/kg, po once a day measured for 16 days: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.474.894.89
526.564.944.94
541.574.634.63
529.544.964.96