Inhibition of human ERG channel expressed in HEK293 cells clamped at -80 mV stimulated +20 mV for 2 sec followed by repolarized to -50 mV for 5 secs b...

Basic Information

ID: ALA5238213

Type: Toxicity

Description: Inhibition of human ERG channel expressed in HEK293 cells clamped at -80 mV stimulated +20 mV for 2 sec followed by repolarized to -50 mV for 5 secs by electrophysiological analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target: HERG(ALA240)

Document: ALA5236589

Inhibition of human ERG channel expressed in HEK293 cells clamped at -80 mV stimulated +20 mV for 2 sec followed by repolarized to -50 mV for 5 secs by electrophysiological analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5238213

IC50

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
462.47	4.89	4.89
541.57	4.63	4.63

Parent Molecular Weight

ALogP

Polar Surface Area

462.47

4.89

541.57

4.63

Inhibition of human ERG channel expressed in HEK293 cells clamped at -80 mV stimulated +20 mV for 2 sec followed by repolarized to -50 mV for 5 secs b...

Basic Information

Activity Charts

Compound Summary