Basic Information
ID: ALA5238555
Type: Binding
Description: Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of TNF-alpha induced NF-kappaB signalling incubated for 18 hrs by dual-luciferase reporter based assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA5238555
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.47 | 1.90 | 1.90 |
| 591.49 | 5.76 | 5.76 |
| 505.42 | 5.70 | 5.70 |
| 680.40 | 5.98 | 5.98 |
| 446.91 | 4.34 | 4.34 |
| 538.98 | 6.07 | 6.07 |
| 612.60 | 4.27 | 4.27 |
| 414.53 | 3.80 | 3.80 |
| 408.91 | 3.76 | 3.76 |
| 426.52 | 2.38 | 2.38 |
| 477.01 | 5.11 | 5.11 |
| 630.79 | 6.21 | 6.21 |
| 531.03 | 5.07 | 5.07 |
| 484.88 | 5.35 | 5.35 |
| 527.09 | 6.39 | 6.39 |
| 412.47 | 3.68 | 3.68 |
| 572.62 | 4.20 | 4.20 |
| 638.68 | 4.03 | 4.03 |
| 471.97 | 4.45 | 4.45 |
| 427.44 | 3.58 | 3.58 |
| 634.82 | 7.05 | 7.05 |
| 424.48 | 3.61 | 3.61 |
| 529.01 | 4.84 | 4.84 |
| 503.00 | 5.50 | 5.50 |
| 440.52 | 4.30 | 4.30 |
| 450.44 | 4.69 | 4.69 |
| 407.45 | 3.55 | 3.55 |
| 456.61 | 4.97 | 4.97 |
| 400.43 | 3.81 | 3.81 |
| 477.03 | 5.32 | 5.32 |
| 460.94 | 4.64 | 4.64 |
| 432.50 | 4.83 | 4.83 |
| 425.47 | 2.77 | 2.77 |
| 470.98 | 5.05 | 5.05 |
| 534.66 | 4.58 | 4.58 |
| 475.57 | 4.89 | 4.89 |
| 436.53 | 4.55 | 4.55 |
| 521.04 | 6.20 | 6.20 |
| 582.66 | 4.47 | 4.47 |
| 550.66 | 5.07 | 5.07 |
| 461.88 | 4.24 | 4.24 |
| 438.55 | 5.02 | 5.02 |
| 488.97 | 5.19 | 5.19 |
| 434.95 | 4.15 | 4.15 |
| 412.47 | 3.68 | 3.68 |
| 524.58 | 3.25 | 3.25 |
| 658.60 | 6.49 | 6.49 |
| 460.94 | 4.64 | 4.64 |
| 472.95 | 3.84 | 3.84 |
| 522.60 | 4.46 | 4.46 |
| 550.66 | 4.74 | 4.74 |
| 410.50 | 3.86 | 3.86 |
| 458.54 | 5.34 | 5.34 |
| 501.00 | 5.06 | 5.06 |
| 674.80 | 7.79 | 7.79 |
| 438.55 | 4.97 | 4.97 |
| 382.44 | 3.67 | 3.67 |
| 482.62 | 3.94 | 3.94 |
| 558.58 | 4.74 | 4.74 |
| 634.78 | 6.89 | 6.89 |
| 388.47 | 3.73 | 3.73 |
| 485.01 | 5.36 | 5.36 |
| 450.56 | 4.71 | 4.71 |
| 437.95 | 3.89 | 3.89 |