Basic Information
ID: ALA5238628
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells to EC50 for antiviral activity against HIV-1 RES056 harboring RT K103N/Y181C double mutant infected in human MT4 cells
Activity Charts
Bioactivity
Activity Types for Assay ALA5238628
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.29 | 4.72 | 4.72 |
| 366.43 | 4.99 | 4.99 |
| 506.58 | 5.91 | 5.91 |
| 474.55 | 6.65 | 6.65 |
| 544.61 | 6.77 | 6.77 |
| 562.60 | 6.90 | 6.90 |
| 514.63 | 6.44 | 6.44 |
| 484.53 | 7.66 | 7.66 |
| 562.60 | 6.90 | 6.90 |
| 467.53 | 6.92 | 6.92 |
| 407.44 | 4.91 | 4.91 |
| 467.53 | 6.92 | 6.92 |
| 506.58 | 5.91 | 5.91 |
| 449.42 | 6.05 | 6.05 |
| 470.60 | 5.64 | 5.64 |
| 536.56 | 6.24 | 6.24 |
| 449.42 | 6.05 | 6.05 |
| 518.57 | 6.10 | 6.10 |
| 611.70 | 5.61 | 5.61 |
| 549.68 | 4.67 | 4.67 |
| 432.42 | 5.31 | 5.31 |
| 567.67 | 4.81 | 4.81 |
| 424.44 | 5.66 | 5.66 |
| 585.66 | 4.95 | 4.95 |
| 544.61 | 6.77 | 6.77 |
| 432.42 | 5.31 | 5.31 |
| 435.37 | 4.87 | 4.87 |
| 410.44 | 4.46 | 4.46 |
| 484.53 | 7.66 | 7.66 |
| 427.44 | 5.21 | 5.21 |
| 593.71 | 5.47 | 5.47 |
| 514.63 | 6.44 | 6.44 |
| 474.55 | 6.65 | 6.65 |
| 491.55 | 7.39 | 7.39 |
| 532.62 | 6.58 | 6.58 |
| 491.55 | 7.39 | 7.39 |
| 488.59 | 5.77 | 5.77 |
| 432.37 | 5.32 | 5.32 |
| 536.56 | 6.24 | 6.24 |
| 500.58 | 5.96 | 5.96 |
| 518.57 | 6.10 | 6.10 |
| 488.59 | 5.77 | 5.77 |
| 418.36 | 4.12 | 4.12 |
| 415.36 | 4.58 | 4.58 |
| 567.67 | 4.81 | 4.81 |
| 585.66 | 4.95 | 4.95 |