Basic Information
ID: ALA5238675
Type: Binding
Description: Antagonist activity at PPAR-gamma (unknown origin) transfected in human HEK293 cells assessed as decrease in rosiglitazone-induced receptor transactivation at 10 uM by dual-luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Peroxisome proliferator-activated receptor gamma(ALA235)
Document: ALA5236599
Antagonist activity at PPAR-gamma (unknown origin) transfected in human HEK293 cells assessed as decrease in rosiglitazone-induced receptor transactivation at 10 uM by dual-luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5238675
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.68 | 3.50 | 3.50 |
| 354.40 | 4.03 | 4.03 |
| 464.95 | 6.35 | 6.35 |
| 465.93 | 5.75 | 5.75 |
| 436.53 | 5.76 | 5.76 |
| 458.55 | 6.26 | 6.26 |
| 498.50 | 6.72 | 6.72 |
| 444.53 | 6.01 | 6.01 |
| 478.52 | 5.85 | 5.85 |
| 498.50 | 6.72 | 6.72 |
| 498.50 | 6.72 | 6.72 |
| 460.53 | 5.71 | 5.71 |
| 460.53 | 5.71 | 5.71 |
| 458.55 | 6.26 | 6.26 |
| 432.48 | 4.49 | 4.49 |
| 436.53 | 5.76 | 5.76 |
| 478.52 | 5.85 | 5.85 |
| 464.95 | 6.35 | 6.35 |
| 464.95 | 6.35 | 6.35 |
| 498.50 | 6.72 | 6.72 |
| 448.49 | 5.84 | 5.84 |
| 465.93 | 5.75 | 5.75 |
| 394.47 | 4.91 | 4.91 |
| 444.53 | 6.01 | 6.01 |
| 432.48 | 4.49 | 4.49 |
| 431.49 | 5.10 | 5.10 |
| 431.49 | 5.10 | 5.10 |
| 464.95 | 6.35 | 6.35 |
| 448.49 | 5.84 | 5.84 |
| 394.47 | 4.91 | 4.91 |