Assay Report Card

Basic Information

ID: ALA5238752

Type: Binding

Description: PROTAC activity at PAK1/CRBN in human MCF7 cells assessed as ERK phosphorylation at Thr202/Tyr204 at 10 nM measured after 24 hrs by immunoblot analysis

Organism: Homo sapiens

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
479.935.065.06
835.336.846.84