Basic Information
ID: ALA5238847
Type: Binding
Description: Inhibition of mouse EGFR D770_N771insNPG mutant stably expressed in mouse BaF3 cells assessed as cell viability incubated for 3 days by Cell Titer-Glo assay
Format: BAO_0000219
Organism: Mus musculus
Cell type: BaF3
Target: Unchecked(ALA612545)
Document: ALA5236603
Inhibition of mouse EGFR D770_N771insNPG mutant stably expressed in mouse BaF3 cells assessed as cell viability incubated for 3 days by Cell Titer-Glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5238847
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.95 | 4.39 | 4.39 |
| 521.03 | 4.32 | 4.32 |
| 499.62 | 4.51 | 4.51 |
| 555.56 | 4.78 | 4.78 |
| 525.66 | 4.92 | 4.92 |
| 585.71 | 5.08 | 5.08 |
| 613.72 | 5.20 | 5.20 |
| 560.10 | 5.57 | 5.57 |
| 599.74 | 5.56 | 5.56 |
| 605.75 | 5.32 | 5.32 |
| 541.66 | 4.50 | 4.50 |
| 571.68 | 4.69 | 4.69 |
| 593.69 | 4.97 | 4.97 |
| 611.75 | 5.61 | 5.61 |
| 592.70 | 5.57 | 5.57 |
| 607.72 | 5.28 | 5.28 |
| 599.74 | 5.32 | 5.32 |
| 597.72 | 5.22 | 5.22 |
| 597.72 | 5.10 | 5.10 |
| 582.71 | 4.28 | 4.28 |
| 549.68 | 4.90 | 4.90 |
| 611.75 | 5.48 | 5.48 |
| 611.75 | 5.87 | 5.87 |
| 581.72 | 5.51 | 5.51 |
| 550.67 | 4.79 | 4.79 |
| 562.07 | 5.02 | 5.02 |
| 633.80 | 6.36 | 6.36 |
| 557.66 | 4.30 | 4.30 |
| 583.69 | 4.71 | 4.71 |
| 576.10 | 5.16 | 5.16 |
| 611.75 | 5.61 | 5.61 |
| 527.63 | 4.37 | 4.37 |