Basic Information
ID: ALA5239321
Type: Binding
Description: PROTAC activity at SOS1/Cereblon in human SW620 cells assessed as ratio of protein degradation normalized to DMSO at 10 uM measured after 6 hrs by immunoblotting analysis
Organism: Homo sapiens
Cell type: SW620
Activity Charts
Bioactivity
Activity Types for Assay ALA5239321
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 594.63 | 3.70 | 3.70 |
| 677.64 | 5.09 | 5.09 |
| 608.66 | 4.01 | 4.01 |
| 773.77 | 4.46 | 4.46 |
| 705.69 | 5.00 | 5.00 |
| 911.93 | 4.70 | 4.70 |
| 919.08 | 8.07 | 8.07 |
| 878.91 | 4.93 | 4.93 |
| 579.61 | 4.10 | 4.10 |
| 662.63 | 4.72 | 4.72 |
| 662.62 | 4.70 | 4.70 |
| 863.89 | 5.35 | 5.35 |
| 795.89 | 4.33 | 4.33 |
| 691.67 | 4.50 | 4.50 |
| 787.80 | 4.85 | 4.85 |