Basic Information
ID: ALA5239338
Type: Binding
Description: PROTAC activity at SOS1/Cereblon in patient-derived CRC organoid MCC19990-013 harboring KRAS G12A mutation assessed as necrosis at 1 uM measured after 24 hrs by hematoxylin and eosin staining based immunohistochemistry
Format: BAO_0000221
Organism: Homo sapiens
Tissue: Colorectal organoid
Target: Cereblon/SOS1(ALA5291681)
Document: ALA5236611
PROTAC activity at SOS1/Cereblon in patient-derived CRC organoid MCC19990-013 harboring KRAS G12A mutation assessed as necrosis at 1 uM measured after 24 hrs by hematoxylin and eosin staining based immunohistochemistry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5239338
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 691.67 | 4.50 | 4.50 |