Basic Information
ID: ALA5239342
Type: Binding
Description: PROTAC activity at SOS1/Cereblon in patient-derived CRC organoid MCC19990-006 harboring KRAS G12C mutation assessed as necrosis measured after 24 hrs by hematoxylin and eosin staining based immunohistochemistry
Organism: Homo sapiens
Tissue: Colorectal organoid
Activity Charts
Bioactivity
Activity Types for Assay ALA5239342
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |
| 691.67 | 4.50 | 4.50 |