Inhibition of recombinant N-terminal GST-tagged human DLK (9 to 111 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylati...

Basic Information

ID: ALA5239394

Type: Binding

Description: Inhibition of recombinant N-terminal GST-tagged human DLK (9 to 111 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylation using MKK4 and ATP as substrate incubated for 1.5 hrs by HTRF analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Sf21

Target: Mitogen-activated protein kinase kinase kinase 12(ALA1908389)

Document: ALA5236614

Inhibition of recombinant N-terminal GST-tagged human DLK (9 to 111 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylation using MKK4 and ATP as substrate incubated for 1.5 hrs by HTRF analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5239394

IC50

Total(22)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
382.40	1.82	1.82
440.40	2.55	2.55
375.38	2.58	2.58
406.39	1.95	1.95
441.39	1.94	1.94
532.51	2.53	2.53
417.42	1.69	1.69
488.50	2.14	2.14
441.39	1.94	1.94
417.42	1.69	1.69
406.39	1.95	1.95
375.38	2.58	2.58
441.39	1.94	1.94
376.37	1.97	1.97
374.39	3.18	3.18
473.48	2.35	2.35
351.41	1.09	1.09
447.45	2.41	2.41
419.41	2.11	2.11
441.39	1.94	1.94
512.47	2.38	2.38
453.48	2.26	2.26