Basic Information
ID: ALA5239752
Type: Binding
Description: Inhibition of BODIPY FL vindoline binding to recombinant human GST-tagged PXR LBD (111 to 434 residues) expressed in baculovirus infected insect cells at 10 uM incubated for 1 mins under shaking condition followed by 60 mins under dark condition by TR-FRET assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5239752
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.34 | 4.76 | 4.76 |
| 438.53 | 4.54 | 4.54 |
| 410.47 | 3.85 | 3.85 |
| 466.58 | 5.32 | 5.32 |
| 520.55 | 6.21 | 6.21 |
| 537.66 | 4.24 | 4.24 |
| 406.53 | 5.30 | 5.30 |
| 509.61 | 5.49 | 5.49 |
| 481.60 | 4.08 | 4.08 |
| 523.63 | 3.85 | 3.85 |
| 471.00 | 5.97 | 5.97 |
| 410.47 | 3.85 | 3.85 |
| 504.55 | 6.33 | 6.33 |
| 407.52 | 4.70 | 4.70 |
| 352.39 | 3.15 | 3.15 |
| 454.55 | 5.45 | 5.45 |
| 419.49 | 4.01 | 4.01 |
| 424.50 | 4.15 | 4.15 |
| 394.48 | 4.14 | 4.14 |
| 409.49 | 3.72 | 3.72 |
| 423.52 | 4.18 | 4.18 |
| 465.60 | 5.35 | 5.35 |
| 410.47 | 3.85 | 3.85 |
| 464.61 | 6.01 | 6.01 |
| 450.58 | 5.62 | 5.62 |
| 482.58 | 4.29 | 4.29 |
| 366.42 | 3.41 | 3.41 |
| 451.53 | 4.10 | 4.10 |
| 421.50 | 3.84 | 3.84 |
| 466.58 | 5.32 | 5.32 |
| 450.58 | 5.44 | 5.44 |
| 466.58 | 5.32 | 5.32 |
| 407.47 | 3.45 | 3.45 |
| 437.54 | 4.21 | 4.21 |
| 485.03 | 6.35 | 6.35 |
| 462.51 | 3.32 | 3.32 |
| 464.61 | 6.01 | 6.01 |
| 394.48 | 4.14 | 4.14 |
| 494.64 | 6.10 | 6.10 |
| 473.37 | 4.91 | 4.91 |
| 465.60 | 5.35 | 5.35 |
| 466.58 | 5.32 | 5.32 |
| 454.55 | 5.45 | 5.45 |
| 428.45 | 2.43 | 2.43 |
| 381.44 | 2.91 | 2.91 |
| 423.52 | 4.18 | 4.18 |
| 520.44 | ||
| 403.44 | 3.64 | 3.64 |
| 424.50 | 4.15 | 4.15 |
| 436.56 | 5.31 | 5.31 |
| 394.48 | 4.14 | 4.14 |
| 464.61 | 6.01 | 6.01 |
| 480.61 | 5.57 | 5.57 |
| 480.61 | 5.71 | 5.71 |
| 451.53 | 4.10 | 4.10 |
| 485.03 | 6.35 | 6.35 |
| 450.58 | 5.62 | 5.62 |
| 495.62 | 4.47 | 4.47 |
| 480.61 | 5.71 | 5.71 |
| 437.54 | 4.71 | 4.71 |
| 480.61 | 5.71 | 5.71 |
| 424.50 | 4.15 | 4.15 |
| 380.45 | 3.97 | 3.97 |
| 466.58 | 5.32 | 5.32 |
| 515.45 | 6.08 | 6.08 |
| 522.69 | 6.88 | 6.88 |
| 437.54 | 4.21 | 4.21 |
| 480.61 | 5.57 | 5.57 |
| 409.49 | 3.72 | 3.72 |
| 480.61 | 5.71 | 5.71 |
| 521.71 | 6.55 | 6.55 |
| 449.51 | 4.05 | 4.05 |
| 485.03 | 6.35 | 6.35 |
| 515.45 | 6.08 | 6.08 |
| 471.00 | 5.97 | 5.97 |
| 436.56 | 5.31 | 5.31 |
| 452.56 | 4.93 | 4.93 |
| 430.53 | 3.69 | 3.69 |