Assay Report Card

Basic Information

ID: ALA5239991

Type: Binding

Description: Protac activity at PDGFRbeta in human U87 cells assessed as reduction in PDGFRbeta protein level at 10 uM preincubated with Carfilzomib for 2hrs followed by compound treatment and measured after 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: U87

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
949.457.947.94