Basic Information
ID: ALA5240232
Type: ADME
Description: Inhibition of recombinant human CYP1B1 assessed as inhibition ratio at 100 nM using 7-ethyl-0-resorufin as substrate incubated for 30 mins in presence of NADPH by EROD assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5240232
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.35 | 3.89 | 3.89 |
| 275.36 | 3.72 | 3.72 |
| 278.34 | 3.54 | 3.54 |
| 362.69 | 5.97 | 5.97 |
| 259.36 | 4.01 | 4.01 |
| 284.37 | 3.88 | 3.88 |
| 277.35 | 4.15 | 4.15 |
| 289.39 | 4.02 | 4.02 |
| 289.39 | 4.02 | 4.02 |
| 319.41 | 4.03 | 4.03 |
| 343.48 | 3.42 | 3.42 |
| 309.42 | 5.16 | 5.16 |
| 357.51 | 3.76 | 3.76 |
| 294.79 | 4.06 | 4.06 |
| 310.41 | 4.56 | 4.56 |
| 293.80 | 4.66 | 4.66 |
| 326.41 | 3.59 | 3.59 |
| 275.36 | 3.72 | 3.72 |
| 274.37 | 3.59 | 3.59 |
| 303.37 | 3.74 | 3.74 |
| 274.37 | 3.59 | 3.59 |
| 304.36 | 3.92 | 3.92 |
| 277.35 | 4.15 | 4.15 |
| 277.35 | 4.15 | 4.15 |
| 325.42 | 4.20 | 4.20 |
| 339.45 | 4.26 | 4.26 |
| 328.25 | 5.32 | 5.32 |
| 289.39 | 4.02 | 4.02 |
| 304.36 | 3.92 | 3.92 |
| 325.42 | 4.20 | 4.20 |
| 293.80 | 4.66 | 4.66 |
| 316.41 | 3.97 | 3.97 |
| 344.47 | 3.85 | 3.85 |
| 310.41 | 4.56 | 4.56 |
| 293.80 | 4.66 | 4.66 |
| 311.79 | 4.80 | 4.80 |
| 319.41 | 4.03 | 4.03 |
| 340.44 | 3.65 | 3.65 |