Basic Information
ID: ALA5240237
Type: ADME
Description: Selectivity index, ratio of IC50 for inhibition of recombinant human CYP1A2 to IC50 for inhibition of recombinant human CYP1B1
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5240237
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.35 | 3.89 | 3.89 |
| 362.69 | 5.97 | 5.97 |
| 473.00 | 6.31 | 6.31 |
| 449.61 | 5.47 | 5.47 |
| 432.40 | 7.55 | 7.55 |
| 381.50 | 6.38 | 6.38 |
| 405.33 | 6.38 | 6.38 |
| 395.53 | 6.94 | 6.94 |
| 289.39 | 4.02 | 4.02 |
| 420.56 | 5.51 | 5.51 |
| 423.56 | 6.26 | 6.26 |
| 450.59 | 5.52 | 5.52 |
| 429.95 | 6.35 | 6.35 |
| 480.45 | 8.65 | 8.65 |
| 420.52 | 5.57 | 5.57 |
| 418.37 | 7.29 | 7.29 |
| 449.56 | 5.71 | 5.71 |
| 353.45 | 5.82 | 5.82 |
| 409.54 | 6.00 | 6.00 |
| 455.01 | 6.17 | 6.17 |
| 368.46 | 5.52 | 5.52 |
| 405.33 | 6.38 | 6.38 |
| 421.55 | 4.91 | 4.91 |
| 293.80 | 4.66 | 4.66 |
| 405.33 | 6.38 | 6.38 |
| 429.55 | 7.48 | 7.48 |
| 447.94 | 6.49 | 6.49 |
| 421.55 | 4.91 | 4.91 |
| 413.50 | 5.83 | 5.83 |
| 438.55 | 5.65 | 5.65 |
| 438.55 | 5.65 | 5.65 |
| 303.37 | 3.74 | 3.74 |
| 471.61 | 7.36 | 7.36 |
| 455.56 | 5.71 | 5.71 |
| 435.58 | 5.22 | 5.22 |
| 277.35 | 4.15 | 4.15 |
| 277.35 | 4.15 | 4.15 |
| 325.42 | 4.20 | 4.20 |
| 413.50 | 5.83 | 5.83 |
| 339.45 | 4.26 | 4.26 |
| 407.50 | 5.83 | 5.83 |
| 328.25 | 5.32 | 5.32 |
| 425.54 | 5.70 | 5.70 |
| 354.44 | 5.21 | 5.21 |
| 404.35 | 6.98 | 6.98 |
| 425.54 | 5.70 | 5.70 |
| 438.79 | 7.64 | 7.64 |
| 422.34 | 7.12 | 7.12 |
| 413.50 | 5.83 | 5.83 |
| 354.44 | 5.21 | 5.21 |
| 344.47 | 3.85 | 3.85 |
| 354.44 | 5.21 | 5.21 |
| 413.50 | 5.83 | 5.83 |
| 293.80 | 4.66 | 4.66 |
| 395.51 | 5.69 | 5.69 |
| 429.95 | 6.35 | 6.35 |
| 319.41 | 4.03 | 4.03 |
| 340.44 | 3.65 | 3.65 |
| 421.55 | 4.91 | 4.91 |