Basic Information
ID: ALA5240296
Type: ADME
Description: Hydrolytic stability in mouse liver microsomes assessed as esterase-mediated compound hydrolysis by measuring residual substrate activity incubated for 30 mins by LC-HRMS analysis
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5240296
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 136.15 | 1.47 | 1.47 |
| 235.28 | 1.76 | 1.76 |
| 325.47 | 4.16 | 4.16 |
| 356.26 | 3.18 | 3.18 |
| 339.44 | 4.12 | 4.12 |
| 164.20 | 2.09 | 2.09 |
| 311.81 | 3.44 | 3.44 |
| 307.39 | 2.79 | 2.79 |
| 303.40 | 3.18 | 3.18 |
| 304.17 | 3.06 | 3.06 |
| 215.29 | 1.49 | 1.49 |
| 347.50 | 4.27 | 4.27 |
| 305.42 | 3.40 | 3.40 |
| 257.37 | 2.52 | 2.52 |
| 283.75 | 2.72 | 2.72 |
| 271.40 | 3.05 | 3.05 |
| 337.73 | 3.43 | 3.43 |
| 345.83 | 4.15 | 4.15 |
| 361.18 | 2.36 | 2.36 |
| 652.83 | 7.61 | 7.61 |
| 339.44 | 4.12 | 4.12 |
| 311.38 | 3.50 | 3.50 |
| 263.29 | 1.33 | 1.33 |
| 307.39 | 2.55 | 2.55 |
| 314.18 | 2.52 | 2.52 |
| 341.41 | 3.51 | 3.51 |
| 277.36 | 2.64 | 2.64 |
| 271.26 | 2.04 | 2.04 |
| 318.20 | 2.99 | 2.99 |
| 342.23 | 3.14 | 3.14 |
| 291.39 | 2.71 | 2.71 |
| 319.45 | 4.10 | 4.10 |
| 325.41 | 3.81 | 3.81 |
| 291.39 | 3.09 | 3.09 |
| 355.56 | 5.39 | 5.39 |
| 387.48 | 5.17 | 5.17 |
| 327.81 | 2.96 | 2.96 |
| 293.41 | 2.66 | 2.66 |
| 249.31 | 2.07 | 2.07 |
| 322.36 | 2.69 | 2.69 |
| 328.21 | 2.83 | 2.83 |
| 263.34 | 2.37 | 2.37 |
| 596.72 | 6.38 | 6.38 |
| 297.35 | 2.78 | 2.78 |
| 277.36 | 2.78 | 2.78 |
| 269.73 | 2.41 | 2.41 |
| 311.38 | 3.43 | 3.43 |