Basic Information
ID: ALA5240361
Type: Binding
Description: Synergistic agonist activity at human HIF-2alpha expressed in human Hep3B cells assessed as induction of EPO transcription at 5 uM pretreated with FG4592 followed by compound addition and measured after 12 hrs by qRT-PCR analysis
Organism: Homo sapiens
Cell type: Hep3B
Activity Charts
Bioactivity
Activity Types for Assay ALA5240361
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.30 | 3.27 | 3.27 |
| 394.30 | 4.29 | 4.29 |
| 408.32 | 4.31 | 4.31 |
| 294.28 | 2.53 | 2.53 |
| 395.28 | 4.25 | 4.25 |
| 318.35 | 2.26 | 2.26 |
| 341.35 | 1.91 | 1.91 |
| 373.18 | 3.29 | 3.29 |
| 473.19 | 5.05 | 5.05 |
| 294.28 | 2.53 | 2.53 |
| 346.32 | 1.64 | 1.64 |
| 393.31 | 4.92 | 4.92 |
| 419.31 | 4.16 | 4.16 |
| 473.19 | 5.05 | 5.05 |
| 351.31 | 3.14 | 3.14 |
| 326.30 | 3.27 | 3.27 |