Basic Information
ID: ALA5240415
Type: ADME
Description: Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in the presence of NADPH by LC/MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 3A4(ALA340)
Document: ALA5236642
Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in the presence of NADPH by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5240415
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.35 | 3.80 | 3.80 |
| 433.34 | 4.17 | 4.17 |