Time dependent inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate in the presence of NADPH by LC/MS/MS analysis

Basic Information

ID: ALA5240416

Type: ADME

Description: Time dependent inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate in the presence of NADPH by LC/MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  Cytochrome P450 2C9(ALA3397)

Document:  ALA5236642

Time dependent inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate in the presence of NADPH by LC/MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
445.353.803.80
433.344.174.17