Basic Information
ID: ALA5240449
Type: Binding
Description: Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of fluorescein labeled corepressor NCOR2 Smrt-ID2 peptide to PPARgamma LBD incubated for 24 hrs by LanthaScreen TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Peroxisome proliferator-activated receptor gamma(ALA235)
Document: ALA5236643
Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of fluorescein labeled corepressor NCOR2 Smrt-ID2 peptide to PPARgamma LBD incubated for 24 hrs by LanthaScreen TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5240449
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.85 | 5.71 | 5.71 |
| 570.94 | 6.29 | 6.29 |
| 518.92 | 4.48 | 4.48 |
| 378.86 | 4.83 | 4.83 |
| 492.88 | 4.62 | 4.62 |
| 364.83 | 4.52 | 4.52 |
| 500.86 | 5.30 | 5.30 |
| 400.81 | 4.80 | 4.80 |
| 433.82 | 4.64 | 4.64 |
| 364.83 | 4.52 | 4.52 |
| 432.83 | 5.54 | 5.54 |
| 549.94 | 7.06 | 7.06 |
| 394.86 | 4.53 | 4.53 |
| 489.88 | 4.76 | 4.76 |
| 399.28 | 5.18 | 5.18 |
| 409.28 | 4.63 | 4.63 |
| 396.85 | 4.97 | 4.97 |
| 476.88 | 5.17 | 5.17 |
| 348.38 | 4.01 | 4.01 |
| 378.86 | 4.83 | 4.83 |
| 382.82 | 4.66 | 4.66 |
| 382.82 | 4.66 | 4.66 |
| 378.86 | 4.83 | 4.83 |
| 399.28 | 5.18 | 5.18 |
| 419.79 | 4.33 | 4.33 |