Protac activity at CRBN/BRD4 in human MM1.S cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.18 uM incubate...

Basic Information

ID: ALA5240534

Type: Binding

Description: Protac activity at CRBN/BRD4 in human MM1.S cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.18 uM incubated for 3 hrs by Western blot analysis relative to control

Format: BAO_0000219

Organism: Homo sapiens

Cell type: MM1.S

Target:  Cereblon/Bromodomain-containing protein 4(ALA4296138)

Document:  ALA5236646

Protac activity at CRBN/BRD4 in human MM1.S cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.18 uM incubated for 3 hrs by Western blot analysis relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
799.314.074.07
847.405.865.86