Assay Report Card

Basic Information

ID: ALA5240541

Type: Binding

Description: Protac activity at CRBN/BRD4 in human MV4-11 cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.09 uM incubated for 3 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: MV4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
785.283.683.68
861.385.505.50
874.425.815.81
819.345.085.08
847.355.115.11