Assay Report Card

Basic Information

ID: ALA5240610

Type: Functional

Description: Antileishmanial activity against Leishmania donovani MHOM/IN/Dd8 promastigotes infected in PMA-differentiated human THP-1 cells assessed as increase in Nrf2-dependent CYP450 gene expression at 10 uM incubated for 18 hrs by RNA-seq analysis

Organism: Leishmania donovani

Strain: MHOM/IN/Dd8

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
177.291.251.25