Basic Information
ID: ALA5240760
Type: Functional
Description: Antiproliferative activity against human NCI-H1975 cells overexpressing EGFR L858R/T790M mutant assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA5240760
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.65 | 2.15 | 2.15 |
| 626.73 | 1.34 | 1.34 |
| 624.75 | 2.55 | 2.55 |
| 667.86 | 2.40 | 2.40 |
| 638.78 | 2.56 | 2.56 |
| 638.78 | 2.56 | 2.56 |
| 624.75 | 2.55 | 2.55 |
| 625.74 | 1.94 | 1.94 |
| 635.78 | 3.22 | 3.22 |
| 635.78 | 3.22 | 3.22 |
| 625.74 | 1.55 | 1.55 |
| 643.80 | 1.55 | 1.55 |
| 674.81 | 3.70 | 3.70 |
| 636.76 | 2.61 | 2.61 |
| 636.76 | 2.61 | 2.61 |
| 636.76 | 2.61 | 2.61 |
| 636.76 | 2.61 | 2.61 |
| 638.78 | 2.56 | 2.56 |