Basic Information
ID: ALA5241960
Type: Binding
Description: Inverse agonist activity at human GAL4-fused RORgammat LBD (262 to 507 residues) transfected in HEK293T cell assessed as maxima inhibition measured after 24 hrs by dual luciferase assay relative to control
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA5241960
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.52 | 5.38 | 5.38 |
| 398.48 | 5.21 | 5.21 |
| 609.65 | 7.45 | 7.45 |
| 551.71 | 6.90 | 6.90 |
| 581.69 | 5.82 | 5.82 |
| 541.65 | 6.17 | 6.17 |
| 605.68 | 7.61 | 7.61 |
| 524.65 | 5.43 | 5.43 |
| 622.79 | 6.73 | 6.73 |
| 439.52 | 5.12 | 5.12 |
| 622.79 | 6.73 | 6.73 |
| 450.59 | 5.25 | 5.25 |
| 487.63 | 5.71 | 5.71 |
| 458.59 | 4.48 | 4.48 |
| 537.69 | 6.23 | 6.23 |
| 466.58 | 5.53 | 5.53 |
| 609.65 | 7.45 | 7.45 |
| 464.49 | 5.97 | 5.97 |
| 523.66 | 6.03 | 6.03 |
| 591.66 | 7.05 | 7.05 |
| 537.69 | 6.34 | 6.34 |
| 503.67 | 6.18 | 6.18 |
| 529.71 | 6.57 | 6.57 |
| 475.61 | 5.40 | 5.40 |
| 601.75 | 5.44 | 5.44 |
| 541.65 | 6.17 | 6.17 |
| 551.71 | 6.54 | 6.54 |
| 559.64 | 6.31 | 6.31 |
| 567.71 | 6.60 | 6.60 |
| 489.64 | 5.64 | 5.64 |
| 501.65 | 5.79 | 5.79 |
| 567.71 | 6.60 | 6.60 |
| 524.65 | 5.43 | 5.43 |
| 551.71 | 6.90 | 6.90 |
| 555.68 | 6.37 | 6.37 |
| 416.47 | 5.35 | 5.35 |
| 503.67 | 6.03 | 6.03 |
| 489.64 | 5.79 | 5.79 |
| 472.61 | 4.62 | 4.62 |
| 475.61 | 5.57 | 5.57 |
| 551.71 | 6.90 | 6.90 |
| 541.65 | 6.17 | 6.17 |
| 551.71 | 6.90 | 6.90 |
| 524.65 | 5.43 | 5.43 |