Basic Information
ID: ALA5241966
Type: Binding
Description: Binding affinity to human RORgamma LBD (262 to 507 residues) expressed in Escherichia coli BL21(DE3) cells assessed as thermal stabilization by measuring change in melting temperature at 200 uM by thermal shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5241966
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.52 | 5.38 | 5.38 |
| 398.48 | 5.21 | 5.21 |
| 609.65 | 7.45 | 7.45 |
| 412.51 | 5.35 | 5.35 |
| 551.71 | 6.90 | 6.90 |
| 581.69 | 5.82 | 5.82 |
| 541.65 | 6.17 | 6.17 |
| 403.46 | 5.36 | 5.36 |
| 605.68 | 7.61 | 7.61 |
| 524.65 | 5.43 | 5.43 |
| 622.79 | 6.73 | 6.73 |
| 439.52 | 5.12 | 5.12 |
| 622.79 | 6.73 | 6.73 |
| 439.52 | 5.12 | 5.12 |
| 450.59 | 5.25 | 5.25 |
| 425.49 | 4.98 | 4.98 |
| 438.53 | 4.91 | 4.91 |
| 487.63 | 5.71 | 5.71 |
| 458.59 | 4.48 | 4.48 |
| 537.69 | 6.23 | 6.23 |
| 466.58 | 5.53 | 5.53 |
| 609.65 | 7.45 | 7.45 |
| 452.56 | 5.00 | 5.00 |
| 464.49 | 5.97 | 5.97 |
| 425.49 | 4.98 | 4.98 |
| 523.66 | 6.03 | 6.03 |
| 591.66 | 7.05 | 7.05 |
| 537.69 | 6.34 | 6.34 |
| 439.52 | 5.12 | 5.12 |
| 503.67 | 6.18 | 6.18 |
| 452.56 | 5.00 | 5.00 |
| 529.71 | 6.57 | 6.57 |
| 475.61 | 5.40 | 5.40 |
| 601.75 | 5.44 | 5.44 |
| 541.65 | 6.17 | 6.17 |
| 551.71 | 6.54 | 6.54 |
| 559.64 | 6.31 | 6.31 |
| 567.67 | 5.73 | 5.73 |
| 567.71 | 6.60 | 6.60 |
| 489.64 | 5.64 | 5.64 |
| 501.65 | 5.79 | 5.79 |
| 567.71 | 6.60 | 6.60 |
| 524.65 | 5.43 | 5.43 |
| 551.71 | 6.90 | 6.90 |
| 555.68 | 6.37 | 6.37 |
| 416.47 | 5.35 | 5.35 |
| 503.67 | 6.03 | 6.03 |
| 489.64 | 5.79 | 5.79 |
| 472.61 | 4.62 | 4.62 |
| 475.61 | 5.57 | 5.57 |
| 462.52 | 6.23 | 6.23 |
| 551.71 | 6.90 | 6.90 |
| 541.65 | 6.17 | 6.17 |
| 551.71 | 6.90 | 6.90 |
| 524.65 | 5.43 | 5.43 |
| 436.60 | 6.37 | 6.37 |