Basic Information
ID: ALA5242438
Type: Binding
Description: Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis
Organism: Homo sapiens
Cell type: MDA-MB-231
Activity Charts
Bioactivity
Activity Types for Assay ALA5242438
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 537.98 | 4.59 | 4.59 |
| 457.51 | 4.15 | 4.15 |
| 443.48 | 3.84 | 3.84 |
| 435.50 | 4.21 | 4.21 |
| 407.45 | 3.59 | 3.59 |
| 503.54 | 3.94 | 3.94 |
| 443.48 | 3.84 | 3.84 |
| 428.47 | 4.13 | 4.13 |
| 381.45 | 3.97 | 3.97 |
| 620.68 | 2.92 | 2.92 |
| 767.90 | 6.73 | 6.73 |
| 387.48 | 5.59 | 5.59 |
| 395.46 | 5.58 | 5.58 |
| 429.46 | 3.53 | 3.53 |
| 401.51 | 5.90 | 5.90 |
| 429.50 | 5.51 | 5.51 |
| 443.48 | 3.84 | 3.84 |
| 421.92 | 6.25 | 6.25 |
| 428.47 | 4.13 | 4.13 |
| 428.47 | 4.13 | 4.13 |
| 459.48 | 3.54 | 3.54 |
| 431.51 | 5.12 | 5.12 |
| 472.52 | 4.45 | 4.45 |
| 405.47 | 5.73 | 5.73 |
| 473.51 | 3.85 | 3.85 |
| 429.46 | 3.53 | 3.53 |
| 428.47 | 4.13 | 4.13 |
| 428.47 | 4.13 | 4.13 |
| 401.51 | 5.90 | 5.90 |
| 421.92 | 6.25 | 6.25 |
| 473.51 | 3.93 | 3.93 |
| 720.80 | 4.48 | 4.48 |
| 399.44 | 4.11 | 4.11 |
| 429.50 | 5.51 | 5.51 |
| 437.54 | 6.75 | 6.75 |
| 427.48 | 4.74 | 4.74 |
| 445.47 | 4.88 | 4.88 |
| 407.45 | 3.59 | 3.59 |
| 609.66 | 5.00 | 5.00 |
| 429.50 | 5.51 | 5.51 |
| 446.31 | 4.89 | 4.89 |
| 502.55 | 3.97 | 3.97 |
| 431.51 | 5.12 | 5.12 |
| 456.37 | 6.90 | 6.90 |
| 460.47 | 2.93 | 2.93 |
| 427.48 | 4.74 | 4.74 |
| 459.48 | 3.54 | 3.54 |
| 377.42 | 3.59 | 3.59 |
| 1461.70 | ||
| 654.66 | 4.91 | 4.91 |
| 451.57 | 7.05 | 7.05 |
| 405.47 | 5.73 | 5.73 |
| 413.47 | 4.42 | 4.42 |
| 439.53 | 4.60 | 4.60 |
| 428.47 | 4.13 | 4.13 |
| 431.51 | 5.12 | 5.12 |
| 415.53 | 6.16 | 6.16 |
| 437.52 | 4.98 | 4.98 |
| 456.37 | 6.90 | 6.90 |
| 431.51 | 5.12 | 5.12 |
| 443.48 | 3.84 | 3.84 |
| 443.48 | 3.84 | 3.84 |
| 458.50 | 4.14 | 4.14 |
| 473.59 | 6.29 | 6.29 |
| 443.48 | 3.84 | 3.84 |
| 429.50 | 5.51 | 5.51 |
| 450.34 | 5.28 | 5.28 |
| 437.54 | 6.75 | 6.75 |
| 431.51 | 5.12 | 5.12 |
| 471.54 | 4.48 | 4.48 |
| 428.47 | 4.13 | 4.13 |
| 427.48 | 4.74 | 4.74 |
| 442.50 | 4.44 | 4.44 |