Basic Information
ID: ALA5242455
Type: Binding
Description: Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis
Organism: Homo sapiens
Cell type: SNU-398
Activity Charts
Bioactivity
Activity Types for Assay ALA5242455
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.54 | 1.10 | 1.10 |
| 515.51 | 2.12 | 2.12 |
| 537.98 | 4.59 | 4.59 |
| 443.48 | 3.84 | 3.84 |
| 459.48 | 3.54 | 3.54 |
| 458.50 | 4.14 | 4.14 |