Basic Information
ID: ALA5242986
Type: Binding
Description: Uncompetitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells assessed as decrease in Km and Vmax of ATP using varying concentrations of ATP and 250 ug/ml yeast RNA as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 1 to 7 hrs by Malachite green ATPase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5242986
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.33 | 6.97 | 6.97 |
| 416.43 | 6.11 | 6.11 |