Basic Information
ID: ALA5242988
Type: Binding
Description: Competitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells assessed as decrease in Km with constant Vmax of RNA using 250 uM ATP and varying concentration of yeast RNA as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 1 to 7 hrs by Malachite green ATPase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5242988
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.33 | 6.97 | 6.97 |
| 416.43 | 6.11 | 6.11 |