Basic Information
ID: ALA5243015
Type: Binding
Description: Inhibition of recombinant full length His-tagged PIP4K2A (unknown origin) expressed in sf21 assessed as reduction in PI4,5P2 production preincubated for 20 mins followed by substrate addition and measured after 60 mins using Dic8-PI5P as substrate in presence of 10 uM ATP by HTRF assay
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA5243015
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.48 | 5.56 | 5.56 |
| 421.50 | 4.82 | 4.82 |
| 366.42 | 4.82 | 4.82 |
| 463.54 | 4.91 | 4.91 |
| 425.47 | 4.65 | 4.65 |
| 450.55 | 4.58 | 4.58 |
| 467.53 | 4.15 | 4.15 |
| 479.58 | 5.51 | 5.51 |
| 450.50 | 4.96 | 4.96 |
| 451.53 | 4.66 | 4.66 |
| 436.52 | 4.55 | 4.55 |
| 485.98 | 5.56 | 5.56 |
| 438.49 | 5.12 | 5.12 |
| 382.22 | 2.83 | 2.83 |
| 455.49 | 4.66 | 4.66 |
| 396.25 | 3.22 | 3.22 |
| 471.95 | 5.17 | 5.17 |
| 451.53 | 4.91 | 4.91 |
| 437.50 | 4.52 | 4.52 |
| 457.48 | 5.45 | 5.45 |
| 479.58 | 5.55 | 5.55 |
| 411.26 | 4.21 | 4.21 |
| 441.92 | 5.16 | 5.16 |
| 422.49 | 4.21 | 4.21 |
| 475.47 | 5.53 | 5.53 |
| 452.51 | 5.51 | 5.51 |
| 441.92 | 5.16 | 5.16 |
| 422.49 | 4.21 | 4.21 |
| 410.28 | 3.61 | 3.61 |
| 439.49 | 4.96 | 4.96 |
| 479.58 | 5.69 | 5.69 |
| 422.49 | 4.21 | 4.21 |
| 460.90 | 5.90 | 5.90 |
| 422.49 | 4.21 | 4.21 |
| 425.47 | 4.65 | 4.65 |
| 437.50 | 4.52 | 4.52 |
| 409.29 | 4.08 | 4.08 |
| 449.56 | 5.63 | 5.63 |
| 437.50 | 4.00 | 4.00 |
| 436.52 | 4.90 | 4.90 |
| 437.50 | 4.00 | 4.00 |
| 455.49 | 4.66 | 4.66 |
| 529.62 | 4.50 | 4.50 |
| 541.68 | 5.51 | 5.51 |
| 414.47 | 4.64 | 4.64 |
| 396.25 | 2.85 | 2.85 |
| 421.50 | 4.82 | 4.82 |
| 515.56 | 5.81 | 5.81 |
| 351.41 | 5.23 | 5.23 |
| 437.50 | 5.50 | 5.50 |
| 555.66 | 5.03 | 5.03 |
| 425.47 | 4.65 | 4.65 |
| 437.50 | 4.52 | 4.52 |
| 459.91 | 5.30 | 5.30 |
| 441.92 | 5.16 | 5.16 |
| 410.28 | 3.61 | 3.61 |