Basic Information
ID: ALA5243071
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of ovine COX-1 to IC50 for inhibition of human recombinant COX-2
Activity Charts
Bioactivity
Activity Types for Assay ALA5243071
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 381.38 | 3.51 | 3.51 |
| 439.92 | 4.52 | 4.52 |
| 422.45 | 2.39 | 2.39 |
| 344.47 | 3.86 | 3.86 |
| 380.41 | 2.13 | 2.13 |
| 459.91 | 5.56 | 5.56 |
| 277.29 | 1.95 | 1.95 |
| 349.35 | 3.00 | 3.00 |
| 336.40 | 2.07 | 2.07 |
| 366.42 | 2.08 | 2.08 |
| 471.95 | 5.43 | 5.43 |
| 459.91 | 5.56 | 5.56 |
| 425.47 | 4.91 | 4.91 |
| 455.95 | 5.73 | 5.73 |
| 379.38 | 3.01 | 3.01 |
| 292.35 | 1.76 | 1.76 |
| 441.92 | 5.42 | 5.42 |
| 276.35 | 2.06 | 2.06 |
| 401.92 | 6.08 | 6.08 |
| 318.38 | 2.44 | 2.44 |
| 443.46 | 5.05 | 5.05 |
| 465.56 | 4.88 | 4.88 |
| 328.42 | 3.29 | 3.29 |
| 453.95 | 4.91 | 4.91 |
| 423.47 | 4.00 | 4.00 |
| 407.48 | 4.77 | 4.77 |
| 306.33 | 2.57 | 2.57 |
| 366.38 | 2.58 | 2.58 |
| 344.47 | 3.69 | 3.69 |
| 308.41 | 2.80 | 2.80 |
| 498.40 | 5.01 | 5.01 |
| 437.50 | 4.78 | 4.78 |
| 320.37 | 2.88 | 2.88 |
| 306.37 | 2.06 | 2.06 |
| 362.39 | 2.37 | 2.37 |
| 532.44 | 4.02 | 4.02 |
| 469.95 | 4.52 | 4.52 |
| 437.50 | 4.39 | 4.39 |
| 332.41 | 2.75 | 2.75 |
| 476.37 | 6.08 | 6.08 |
| 487.99 | 3.91 | 3.91 |
| 453.50 | 4.01 | 4.01 |
| 282.33 | 2.62 | 2.62 |
| 336.83 | 3.39 | 3.39 |
| 392.42 | 2.38 | 2.38 |
| 484.38 | 4.62 | 4.62 |
| 259.33 | 3.10 | 3.10 |
| 336.35 | 2.58 | 2.58 |
| 319.37 | 2.62 | 2.62 |
| 350.38 | 2.12 | 2.12 |
| 345.45 | 2.80 | 2.80 |
| 355.24 | 2.82 | 2.82 |
| 514.40 | 4.63 | 4.63 |
| 303.37 | 2.13 | 2.13 |
| 308.43 | 3.16 | 3.16 |
| 381.28 | 3.50 | 3.50 |
| 289.36 | 3.11 | 3.11 |
| 319.32 | 2.99 | 2.99 |
| 455.49 | 4.92 | 4.92 |
| 421.50 | 5.08 | 5.08 |
| 439.49 | 5.22 | 5.22 |
| 290.37 | 2.36 | 2.36 |
| 292.35 | 1.76 | 1.76 |
| 471.54 | 3.40 | 3.40 |
| 214.28 | 0.70 | 0.70 |
| 425.47 | 4.91 | 4.91 |
| 293.78 | 3.75 | 3.75 |
| 316.41 | 3.05 | 3.05 |
| 441.92 | 5.42 | 5.42 |
| 320.36 | 2.11 | 2.11 |