Basic Information
ID: ALA5243074
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of human COX-1 to IC50 for inhibition of human COX-2
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5243074
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.85 | 4.18 | 4.18 |
| 381.38 | 3.51 | 3.51 |
| 603.04 | 5.53 | 5.53 |
| 604.65 | 4.95 | 4.95 |
| 677.51 | 5.65 | 5.65 |
| 586.58 | 5.02 | 5.02 |
| 319.32 | 1.09 | 1.09 |
| 647.49 | 5.64 | 5.64 |
| 385.45 | 2.54 | 2.54 |
| 586.58 | 5.02 | 5.02 |
| 574.62 | 4.94 | 4.94 |
| 389.86 | 3.18 | 3.18 |
| 289.29 | 1.08 | 1.08 |
| 520.55 | 3.84 | 3.84 |
| 379.37 | 1.11 | 1.11 |
| 604.65 | 4.95 | 4.95 |
| 715.49 | 6.66 | 6.66 |
| 603.04 | 5.53 | 5.53 |
| 307.28 | 1.22 | 1.22 |
| 681.93 | 6.30 | 6.30 |
| 636.46 | 8.29 | 8.29 |
| 697.36 | 8.91 | 8.91 |
| 609.07 | 5.60 | 5.60 |
| 598.62 | 4.89 | 4.89 |
| 604.65 | 4.95 | 4.95 |
| 609.07 | 5.60 | 5.60 |
| 307.28 | 1.22 | 1.22 |
| 349.35 | 1.10 | 1.10 |
| 677.51 | 5.65 | 5.65 |
| 681.93 | 6.30 | 6.30 |
| 648.68 | 6.04 | 6.04 |
| 582.62 | 5.19 | 5.19 |
| 603.04 | 5.53 | 5.53 |
| 653.52 | 5.71 | 5.71 |
| 587.59 | 7.53 | 7.53 |
| 385.45 | 2.54 | 2.54 |
| 653.52 | 5.71 | 5.71 |
| 726.38 | 6.41 | 6.41 |
| 587.59 | 7.53 | 7.53 |
| 592.01 | 8.18 | 8.18 |
| 232.35 | 3.00 | 3.00 |
| 636.46 | 8.29 | 8.29 |
| 587.59 | 7.53 | 7.53 |
| 618.65 | 6.03 | 6.03 |
| 586.58 | 5.02 | 5.02 |
| 648.68 | 6.04 | 6.04 |
| 319.32 | 1.09 | 1.09 |
| 536.55 | 3.54 | 3.54 |
| 604.65 | 4.95 | 4.95 |
| 557.56 | 7.53 | 7.53 |
| 661.52 | 5.95 | 5.95 |
| 415.47 | 2.55 | 2.55 |
| 665.48 | 5.78 | 5.78 |
| 585.42 | 4.29 | 4.29 |
| 248.35 | 2.70 | 2.70 |
| 618.47 | 8.15 | 8.15 |
| 452.60 | 7.88 | 7.88 |
| 557.56 | 7.53 | 7.53 |
| 323.74 | 1.74 | 1.74 |
| 598.62 | 4.89 | 4.89 |
| 636.59 | 5.90 | 5.90 |
| 653.10 | 6.69 | 6.69 |
| 307.28 | 1.22 | 1.22 |
| 648.49 | 8.16 | 8.16 |
| 648.49 | 8.16 | 8.16 |
| 652.91 | 8.80 | 8.80 |
| 665.48 | 5.78 | 5.78 |
| 574.62 | 4.94 | 4.94 |
| 592.01 | 8.18 | 8.18 |
| 697.55 | 6.80 | 6.80 |
| 368.19 | 1.85 | 1.85 |
| 587.59 | 7.53 | 7.53 |
| 665.48 | 5.78 | 5.78 |
| 614.86 |