Basic Information
ID: ALA5244340
Type: Binding
Description: Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5244340
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 630.83 | 5.99 | 5.99 |
| 630.79 | 4.94 | 4.94 |
| 618.78 | 4.45 | 4.45 |
| 632.81 | 4.84 | 4.84 |
| 600.76 | 4.97 | 4.97 |
| 634.78 | 4.07 | 4.07 |
| 562.67 | 2.89 | 2.89 |
| 590.73 | 3.67 | 3.67 |
| 616.76 | 4.55 | 4.55 |
| 634.78 | 3.68 | 3.68 |
| 618.78 | 4.45 | 4.45 |
| 630.79 | 4.59 | 4.59 |
| 636.77 | 4.59 | 4.59 |
| 602.78 | 5.21 | 5.21 |
| 604.75 | 4.06 | 4.06 |
| 604.75 | 4.06 | 4.06 |
| 634.80 | 5.74 | 5.74 |
| 617.75 | 2.57 | 2.57 |
| 618.78 | 4.45 | 4.45 |
| 588.75 | 4.82 | 4.82 |
| 616.76 | 4.55 | 4.55 |
| 632.81 | 4.84 | 4.84 |
| 632.81 | 5.18 | 5.18 |
| 644.82 | 4.98 | 4.98 |
| 477.57 | 3.09 | 3.09 |
| 628.82 | 5.74 | 5.74 |
| 590.73 | 3.67 | 3.67 |
| 630.79 | 4.59 | 4.59 |
| 632.81 | 4.69 | 4.69 |
| 673.86 | 5.17 | 5.17 |
| 660.86 | 5.08 | 5.08 |
| 636.77 | 4.93 | 4.93 |
| 660.82 | 4.22 | 4.22 |
| 659.83 | 4.78 | 4.78 |
| 606.74 | 4.96 | 4.96 |
| 602.74 | 3.81 | 3.81 |
| 604.75 | 4.06 | 4.06 |
| 619.77 | 3.85 | 3.85 |
| 646.83 | 4.69 | 4.69 |
| 604.80 | 4.92 | 4.92 |
| 604.75 | 4.06 | 4.06 |
| 618.78 | 4.45 | 4.45 |
| 608.72 | 3.81 | 3.81 |
| 659.83 | 4.78 | 4.78 |
| 632.81 | 4.84 | 4.84 |
| 620.75 | 3.03 | 3.03 |
| 588.75 | 4.82 | 4.82 |
| 616.76 | 4.20 | 4.20 |
| 632.81 | 4.84 | 4.84 |
| 615.78 | 3.73 | 3.73 |
| 622.74 | 4.20 | 4.20 |
| 594.69 | 3.42 | 3.42 |
| 622.74 | 4.20 | 4.20 |
| 618.78 | 4.79 | 4.79 |
| 604.75 | 4.06 | 4.06 |
| 632.81 | 4.84 | 4.84 |
| 618.78 | 4.45 | 4.45 |
| 633.79 | 4.24 | 4.24 |
| 600.76 | 4.97 | 4.97 |
| 615.78 | 3.73 | 3.73 |
| 560.70 | 4.04 | 4.04 |
| 636.77 | 4.59 | 4.59 |
| 618.78 | 4.45 | 4.45 |
| 659.83 | 3.74 | 3.74 |
| 604.75 | 4.06 | 4.06 |
| 659.83 | 3.74 | 3.74 |
| 632.81 | 4.76 | 4.76 |
| 604.80 | 4.92 | 4.92 |
| 602.78 | 5.21 | 5.21 |
| 646.83 | 5.23 | 5.23 |
| 590.73 | 3.67 | 3.67 |
| 616.76 | 4.20 | 4.20 |
| 576.70 | 3.28 | 3.28 |
| 586.74 | 4.58 | 4.58 |
| 632.81 | 4.76 | 4.76 |
| 604.75 | 4.06 | 4.06 |
| 604.75 | 4.06 | 4.06 |
| 602.78 | 5.21 | 5.21 |
| 677.82 | 4.91 | 4.91 |
| 660.86 | 5.08 | 5.08 |
| 618.78 | 4.45 | 4.45 |
| 648.81 | 4.46 | 4.46 |
| 616.76 | 4.20 | 4.20 |
| 618.78 | 4.79 | 4.79 |
| 622.74 | 4.20 | 4.20 |
| 560.70 | 4.04 | 4.04 |
| 614.79 | 5.35 | 5.35 |
| 602.78 | 4.68 | 4.68 |
| 616.81 | 5.60 | 5.60 |
| 590.73 | 3.67 | 3.67 |
| 618.78 | 4.37 | 4.37 |
| 604.75 | 4.06 | 4.06 |
| 622.74 | 4.20 | 4.20 |
| 608.72 | 3.81 | 3.81 |
| 634.78 | 4.07 | 4.07 |
| 602.74 | 3.81 | 3.81 |
| 648.81 | 4.46 | 4.46 |
| 634.78 | 3.68 | 3.68 |
| 644.82 | 4.98 | 4.98 |
| 663.80 | 4.52 | 4.52 |
| 590.73 | 3.67 | 3.67 |
| 691.85 | 5.30 | 5.30 |
| 616.81 | 5.60 | 5.60 |
| 590.77 | 4.53 | 4.53 |
| 576.70 | 3.28 | 3.28 |
| 588.75 | 4.82 | 4.82 |
| 590.73 | 3.67 | 3.67 |
| 620.75 | 3.68 | 3.68 |