Basic Information
ID: ALA5244342
Type: Binding
Description: Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SEAP reporter gene based spectrophotometry assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-Blue hTLR8
Target: Toll-like receptor 8(ALA5805)
Document: ALA5244202
Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SEAP reporter gene based spectrophotometry assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5244342
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 243.33 | 3.38 | 3.38 |
| 285.37 | 3.76 | 3.76 |
| 311.33 | 4.31 | 4.31 |
| 313.43 | 4.54 | 4.54 |
| 297.31 | 3.92 | 3.92 |
| 258.35 | 2.96 | 2.96 |
| 243.34 | 3.55 | 3.55 |
| 257.36 | 3.77 | 3.77 |
| 257.36 | 3.63 | 3.63 |
| 284.35 | 4.32 | 4.32 |
| 340.41 | 4.44 | 4.44 |
| 382.57 | ||
| 326.39 | 4.05 | 4.05 |
| 271.35 | 3.37 | 3.37 |
| 271.39 | 4.02 | 4.02 |
| 321.43 | 3.17 | 3.17 |
| 215.28 | 2.74 | 2.74 |
| 257.36 | 3.94 | 3.94 |
| 327.45 | 4.93 | 4.93 |
| 323.42 | 4.15 | 4.15 |
| 229.31 | 2.99 | 2.99 |
| 271.39 | 4.16 | 4.16 |