Basic Information
ID: ALA5244347
Type: Binding
Description: Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as induction of SEAP production using nitrophenyl phosphate as substrate incubated for 20 hrs by microplate reader analysis
Organism: Homo sapiens
Cell type: HEK-Blue hTLR8
Activity Charts
Bioactivity
Activity Types for Assay ALA5244347
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.61 | 3.01 | 3.01 |
| 431.58 | 2.35 | 2.35 |
| 427.59 | 3.53 | 3.53 |
| 413.57 | 3.14 | 3.14 |
| 442.61 | 2.29 | 2.29 |
| 456.64 | 2.68 | 2.68 |