Basic Information
ID: ALA5244394
Type: Binding
Description: Inhibition of FLAP in human PMNL cells assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated with enzyme for 15 mins followed by Ca2+ ionophore-A23187 and measured after 10 mins by HPLC analysis
Organism: Homo sapiens
Cell type: PMNL
Activity Charts
Bioactivity
Activity Types for Assay ALA5244394
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.89 | 6.49 | 6.49 |