Basic Information
ID: ALA5244531
Type: Functional
Description: Antimalarial activity against blood stage chloroquine-sensitive Plasmodium falciparum 3D7 infected in erythrocytes assessed as reduction in parasite growth preincubated for 72 hrs followed by addition of [3H]Hypoxanthine and measured after 24 hrs by liquid scintillation counting method
Organism: Plasmodium falciparum
Strain: 3D7
Cell type: Erythrocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA5244531
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.54 | 1.54 |
| 232.24 | 1.42 | 1.42 |
| 369.34 | 1.70 | 1.70 |
| 331.35 | 1.58 | 1.58 |
| 319.34 | 1.27 | 1.27 |
| 416.36 | 1.89 | 1.89 |
| 375.40 | 1.98 | 1.98 |
| 401.44 | 2.37 | 2.37 |
| 319.88 | 4.81 | 4.81 |
| 333.36 | 1.61 | 1.61 |
| 417.39 | 2.90 | 2.90 |
| 365.79 | 2.36 | 2.36 |
| 359.40 | 2.28 | 2.28 |
| 303.32 | -0.08 | -0.08 |
| 261.23 | 1.45 | 1.45 |
| 320.32 | 0.66 | 0.66 |
| 294.31 | 2.78 | 2.78 |
| 392.41 | 2.08 | 2.08 |
| 363.41 | 1.70 | 1.70 |
| 300.29 | 2.65 | 2.65 |
| 288.31 | 1.11 | 1.11 |
| 262.22 | 0.84 | 0.84 |
| 261.25 | 2.35 | 2.35 |
| 362.36 | 0.51 | 0.51 |
| 353.37 | 1.49 | 1.49 |
| 740.76 | 1.54 | 1.54 |