Basic Information
ID: ALA5246483
Type: Binding
Description: Inhibition of human FXIa using S-2366 as chromogenic substrate preincubated with enzyme for 10 mins followed by substrate addition by spectrophotometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5246483
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1241.99 | ||
| 927.97 | 7.04 | 7.04 |
| 857.83 | 5.09 | 5.09 |
| 899.92 | 6.26 | 6.26 |
| 885.89 | 5.87 | 5.87 |
| 871.86 | 5.48 | 5.48 |
| 913.94 | 6.65 | 6.65 |
| 822.78 | 5.08 | 5.08 |
| 782.72 | 4.90 | 4.90 |
| 776.76 | 5.45 | 5.45 |
| 1227.97 | ||
| 804.81 | 6.23 | 6.23 |
| 748.70 | 4.67 | 4.67 |
| 782.72 | 4.90 | 4.90 |
| 1256.02 | ||
| 782.72 | 4.90 | 4.90 |
| 750.68 | 3.52 | 3.52 |
| 832.87 | 7.01 | 7.01 |
| 732.66 | 4.06 | 4.06 |
| 762.73 | 5.06 | 5.06 |
| 782.72 | 4.90 | 4.90 |
| 790.78 | 5.84 | 5.84 |
| 818.84 | 6.62 | 6.62 |
| 748.70 | 4.67 | 4.67 |
| 762.73 | 5.06 | 5.06 |
| 340.29 | 1.77 | 1.77 |
| 1270.05 | ||
| 782.72 | 4.90 | 4.90 |