Assay Report Card

Basic Information

ID: ALA5246511

Type: Binding

Description: Inhibition of human FXIa heparin-binding site of A3 domain harboring K252A,K253A,K255A mutant and heparin-binding site of catalytic domain harboring K529A,R530A,R532A,K535A,K539A mutant using S-2366 as chromogenic substrate preincubated with enzyme for 10 mins followed by substrate addition by spectrophotometric analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
804.816.236.23